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Biotech General Discussion

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BCRX - Bull Thesis

(Updated 10/31/2022)


BULL THESIS SUMMARY

  • BCRX overall corporate and summary

  • Focusing on difficult to develop oral therapies for life threatening and rare diseases, with product drug development group

  • Attractive ~$2.5B valuation for company with approval $250M rev drug that could be $1B at peak, 2 valuable compounds in clinic, and productive oral drug discovery engine

  • Attractive M&A candidate, esp. for big pharma in HAE who could lock up some other further out next-gen players too

  • Unlikely to dilute investors with public offerings because can obtain additional credit if necessary, with Orladeyo revenue as collateral

  • Management has seen failures and recognizes this possibility for its candidates, but proactively works on backup candidates to stay nimble in drug development

MV 9/30/2022


(See below for full updated bull analysis)



BULL THESIS

  • BCRX overall corporate and summary

  • Heavy competition for current and future BCRX drugs will continue to hold down valuation

  • ORLADEYO

  • Orladeyo market opportunity is less than Company’s ~$1B projection

  • GI issues lead to discontinuations or patients sticking with other drugs

  • Lots of competitors for HAE (*1)

  • including approved drugs from Takeda and Behring

  • and clinical stage including several other oral drugs against the same target as OLRLADEYO (PKa) or drugs that may require administration only semi-annually, or curative gene therapies

  • As data is presented for competitive therapies, especially oral with less GI issues, or semi-annual or curative gene therapies, BCRX stock will be hit


MV 9/30/2022


See the bull/bear analysis in our BPIQ Pro Forum post here and the full bull/bear analysis w/ Amp view in our Amp Premium Forum post here. To become a subscriber Learn more here.


#BCRX #ORLADEYO #berotralstat #BCX9930

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