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Biotech General Discussion

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Upcoming Q4 Blood Cancer Readouts

Lots of blood cancer readouts this Q4 📸 👇

Some of them are likely to move big upon readout 👀



We identified 2 movers from the blood cancer readouts this Q4 📈 📉


$SYRS

Tamibarotene / HR-MDS / Phase 3

Mid-Q4 2024 readout guidance


» Ph2 result: Tamibarotene + Azatidine delivered 61% CR/CRi rate in newly diagnosed AML patients with RARA gene overexpression.


» See 📸 👇 for prior results and Ph3 trial design



$SNDX

Revumenib / R/R mNPM1 AML / Phase 2


» Positive Ph2 data could support sNDA filing for revumenib in H1 2025. 📸 👇


» mNPM1: Most frequent genetic alteration in AML

» KMT2Ar: rearrangement in the lysine methyltransferase 2a gene

→ KMT2Ar ALL & AML filing currently under FDA  priority review


» Ph1 results suggest robust efficacy with durable MRDneg responses (100%). 📸 👇





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This article is not investment, tax, or legal advice. Please do your own diligence and seek advice from professional advisors representing your interests.


Article history:

First published 11/01/24 EJV, JD, SK, & AV



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