QURE

AMT-130

Huntington’s Disease

Stage (next event)

Expected Date

Phase 2 (Data)

2021

Catalyst Info & Data Links

TITLE: PTG-300 (Hepcidin Mimetic) for Polycythemia Vera (PV) - Phase 2 Data

  • ClinicalTrials.gov (NCT04120493): Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington Disease


WHAT IS THE CATALYST EVENT?

  • Phase 2 Data


WHEN WILL THE EVENT (OR DID THE EVENT) OCCUR?

  • 2021


PRIOR DATA/EVENTS

PRESS RELEASE

Mechanism of Action

MARKET

  • Huntington’s disease is a rare, inherited neurodegenerative disorder that leads to motor symptoms including chorea, and behavioral abnormalities and cognitive decline resulting in progressive physical and mental deterioration. The disease is an autosomal dominant condition with a disease-causing CAG repeat expansion in the first exon of the huntingtin gene that leads to the production and aggregation of abnormal protein in the brain. Despite the clear etiology of Huntington’s disease, there are no currently approved therapies to delay the onset or to slow the disease’s progression.

Updated by HC

Prior Data (click to view full image)

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Trial Design / Revenue (click to view full image)

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