MRK

rVSVΔG-SARS-CoV-2

COVID-19 Vaccine

Preclinical

Exp Date

TBD

Amp Volatility Score

Catalyst Info & Data Links

TITLE: MRK and IAVI COVID-19 vaccine (rVSVΔG-SARS-CoV-2) - Preclinical Data


WHAT IS THE CATALYST EVENT?

  • Preclinical data


WHEN WILL THE EVENT (OR DID THE EVENT) OCCUR?

  • TBD


PRIOR DATA

PRESS RELEASES

MARKET

MECHANISM OF ACTION/RATIONALE

  • Vesicular stomatitis virus (VSV) is a prototypic enveloped animal virus that has been used extensively to study virus entry, replication and assembly due to its broad host range and robust replication properties in a wide variety of mammalian and insect cells. Studies on VSV assembly led to the creation of a recombinant VSV in which the glycoprotein (G) gene was deleted. (Source

  • The glycoprotein of VSV was replaced by the spike protein of the SARS-CoV-2 (Source)

Prior Data (click to view full image)

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Trial Design / Revenue (click to view full image)

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