Multiple myeloma (Relapsed/Refractory and Front line) | STOMP

Phase 1b/2

Exp Date


Amp Volatility Score

Catalyst Info & Data Links

Potential Catalyst Events

  • TBA

Clinical Trial

  • NCT02343042: Selinexor and Backbone Treatments of Multiple Myeloma Patients (STOMP)

Time Line

Related Links

Prior Work

HC updated 5/22/20


  • Nuclear export inhibitor

  • Inhibits XPO1 (see slide 5), which is believed to impact tumor cells in 3 ways

1. Increases nuclear levels and activation of tumor suppressor proteins
2. Traps oncoprotein mRNA in the nucleus leading to reduced oncoprotein levels
3. Retains activated glucocorticoid receptor in the nucleus

Prior Data (click to view full image)


Trial Design / Revenue (click to view full image)


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