ENTA

MAVYRET (Glecaprevir)

Hepatitis C Virus

Stage (next event)

Expected Date

Quarterly Sales (Approved)

February 5, 2021 (Est)

Catalyst Info & Data Links

TITLE: MAVYRET (Glecaprevir) for Hepatitis C Virus


WHAT IS THE NEXT CATALYST EVENT?

  • Quarterly Sales


WHEN WILL THE EVENT (OR DID THE EVENT) OCCUR?

  • February 5, 2021 (Est)


PRIOR DATA

PRESS RELEASES


Quarter's sales: $23.6M Q3/2020

2021 Revenue guidance: 

  • Research and Development Expense: $145 million to $165 million

  • General and Administrative Expense: $27 million to $33 million



Mechanism of Action

MECHANISM OF ACTION

  • Mavyret is a combination of 2 direct-acting antiviral agents, with distinct mechanisms of action. Glecaprevir is an inhibitor of the HCV NS3/4A protease, which is necessary for the proteolytic cleavage of the HCV encoded polyprotein and for viral replication. Pibrentasvir is an inhibitor of HCV NS5A, which is essential for viral RNA replication and virion assembly.

Updated by JM 

Prior Data (click to view full image)

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Trial Design / Revenue (click to view full image)

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