CARA

Oral Korsuva

Pruritus CKD 3-5

Phase 3 TBA

Exp Date

H2 2020

Amp Volatility Score

Catalyst Info & Data Links

TITLE: Oral Korsuva in Pruritus CKD 3-5


WHAT IS THE CATALYST EVENT?

  • TBD


WHEN WILL THE EVENT (OR DID THE EVENT) OCCUR?

  • TBD


PRIOR DATA/EVENTS


PRESS RELEASE

POSTERS


PRESENTATIONS

PUBLICATIONS

COMPETITORS

MARKET

  • ~7.3 million diagnosed with CKD (IQVIA est)


MECHANISM OF ACTION / RATIONALE

  • Difelikefalin (CR845) is a peripherally restricted, selective kappa opioid receptor agonist that exerts antipruritic effects by means of activation of kappa opioid receptors on peripheral neurons and immune cells. The hydrophilic small-peptide structure restricts passive diffusion across membranes, thereby limiting access to kappa opioid receptors in the central nervous system (Fishbane et al., 2020).

Updated by HC

CARA, Korsuva IV (CR845 IV), Pruritus, CKD

Prior Data (click to view full image)

Chart

Trial Design / Revenue (click to view full image)

Chart

Recent Posts

See What The Community Is Saying - Click To See Full Post

Educational video - Near-term ...

Check out my recent video in our educational forum, which discusses the unfortunate reality of small and mid-cap biopharma investing: near-term dilution. Case studies are provided for CARA and TGTX, ...

CARA DD Update...

Summary 2020 is a big year for oral Korsuva. CARA took a big hit in late 2019 from oral phase 2 data. The second phase 3 readout for IV Korsuva, KALM-II, is set to report out in Q2 ‘20. Overview Cara...

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