Stage (next event)
Catalyst Info & Data Links
TITLE: INOpulse for PH-ILD phase 2b initiation for phase 2b trial
WHAT IS THE NEXT CATALYST EVENT?
Phase 2b Trial
WHEN WILL THE EVENT (OR DID THE EVENT) OCCUR
Mechanism of Action
MECHANISM OF ACTION
Nitric oxide is normally produced in the blood vessel endothelium linings, working on the smooth muscle of the blood vessels to dilate or open the arteries. When nitric oxide enters the smooth muscle cells, it directly activates a chemical called soluble guanylate cyclase (sGC) in these cells. sGC produces another substance called cyclic guanosine monophosphate (GMP). Cyclic GMP then causes the smooth muscle cells to relax, which in turn causes the blood vessels (arteries) to widen or dilate also known as vasodilation.
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Updated by MV
Prior Data (click to view full image)
Trial Design / Revenue (click to view full image)
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