AMRN

Vascepa

Cardiovascular disease (triglyceride lowering)

Stage (next event)

Expected Date

Quarterly Sales (Approved)

February 26, 2021 (Est)

Catalyst Info & Data Links

MECHANISM OF ACTION/RATIONALE

  • Studies suggest that EPA reduces hepatic very low-density lipoprotein triglycerides (VLDL-TG) synthesis and/or secretion and enhances TG clearance from circulating VLDL particles. Potential mechanisms of action include increased β-oxidation; inhibition of acyl-CoA:1,2-diacylglycerol acyltransferase (DGAT); decreased lipogenesis in the liver; and increased plasma lipoprotein lipase activity.

  • FDA Drug Label (slide 5, section 12.1)

MECHANISM OF ACTION/RATIONALE

Updated by EJV (Prior update by HC 11/20/20)

Prior Data (click to view full image)

Chart

Trial Design / Revenue (click to view full image)

Chart

Recent Posts

See what the community is saying - click to see full post

AMRN Litigation Update - 5/19/20 BIO Brief

AMRN - Near-Term Price Acton Depends on Breadth of Label, but Acquisition Chatter and Quarterly Resu

Amarin's U.S. Patent Protection For Vascepa

Congrats Amarin for Major Breakthrough in Treating Cardiovascular Disease

AMRN; a Q3 Pick and Possible Run-Up

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