ACRS

ATI-450

Cytokine Release Syndrom in COVID-19 Patients

Phase 2

Exp Date

H2 2020

Amp Volatility Score

N/A

Catalyst Info & Data Links

TITLE: ATI-450 for Cytokine Release Syndrom in COVID-19 Patients Phase 2 Readout


WHAT IS THE NEXT CATALYST EVENT?

  • Phase 2 Readout


WHEN WILL THE EVENT (OR DID THE EVENT) OCCUR?

  • H2 2020


PRIOR DATA
PRESS RELEASES

MECHANISM OF ACTION

  • ATI-450 is an investigational oral mitogen-activated protein kinase-activated protein kinase 2 (MK2) inhibitor in Phase 2 clinical development. This mechanism leads to the inhibition of multiple cytokines, chemokines, matrix metalloproteases and other inflammatory signals. Key inflammatory cytokines driven by this mechanism include tumor necrosis factor α (TNFα) and interleukin-1α, -1β, -6 and -8 (IL1α, IL1β, IL6 and IL8). Aclaris is developing ATI-450 as a potential treatment for rheumatoid arthritis and other immuno-inflammatory diseases.

Updated by MV

#COVIDtherapeutic #COVIDtherapy #infectiousdisease #ACRS #ATI-450 #ATI450 

Prior Data (click to view full image)

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Trial Design / Revenue (click to view full image)

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