Humanigen Inc.

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Company Profile

We are a clinical stage biopharmaceutical company, developing our immunology and immuno-oncology portfolio of monoclonal antibodies. We are focusing our efforts on the development of our lead product candidate, lenzilumab, our proprietary Humaneered® (“Humaneered”) anti-human granulocyte-macrophage colony-stimulating factor (“GM-CSF”) monoclonal antibody. Lenzilumab is a monoclonal antibody that has been proven in animal models to neutralize GM-CSF.

Drug Pipeline

Click on drug name or indication to see upcoming trial info, prior data, and more general information

Drug | Disease (links)

Stage (next event)

Catalyst Date



Phase 3 (EUA / BLA filing / approval / launch)

Q4 2020


Prevention / treatment of Hyper-inflammation / Cytokine Storm

Phase 3 Topline Data



Prevention/Treatment of Acute GvHD

Phase 2/3 Initiation



Eosinophilic Asthma (EA)

Phase 3 Initiation



Efficacy/Toxicity Linkage
Prophylaxis as sequenced therapy with Yescarta (CAR-T) in r/r DLBCL

Phase 1b/2 data



Relapsed or Refractory Diffuse Large B-Cell Lymphoma / RR DLBCL

Phase 1b (Results)

Q4 2020

Ifabotuzumab | KB004

Glioblastoma Multiforme (GBM)

Phase 1

H1 2021

Recent Posts

See what the community is saying - click to see full post

HGEN - Humanigen Announces Cooperative Research and Development Agreement with the Department of Defense to De

HGEN - Humanigen Announces Interim Phase 3 Data of Lenzilumab™ in Patients Hospitalized with COVID-19

HGEN - Lenzilumab COVID-19 Case-Control Study Published in Mayo Clinic Proceedings Journal

HGEN - Lenzilumab COVID-19 Case-Control Study Published in Mayo Clinic Proceedings Journal

Are IL-6 Inhibitors still alive as a Covid Treatment?

Do failures of IL-6 blockers read thru to HGEN's Lenzilumab?

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